What is cannabidivarin (CBDV) and is it the next big thing?
What is cannabidivarin (CBDV) and is it the next big thing?
One of the most exciting things to discuss when it comes to cannabis is cannabinoids: yes, these excellent chemical compounds in the cannabis plant. But most of the conversations about cannabinoids always depend on THC and CBD as these are the most widely used and most prominent cannabinoids known.
But there are many other cannabinoids in the cannabis plant that have the potential to have a huge impact on the lives of those who use cannabis. One such cannabinoid is cannabidivarin (CBDV).
We will learn more about this potent cannabinoid, understand the benefits it offers, and how it works. The cannabis plant is an attractive component to consider because of the myriad of benefits it offers users, but this article focuses on cannabidivarin; What makes this chemical so unique?
What is CBDV?
Cannabidivarin is a secondary cannabinoid that is often found in lower concentrations as opposed to THC and CBD in high concentrations. It is a non-intoxicating cannabinoid that does not cause a euphoric “high” when used by cannabis enthusiasts.
CBDV also doesn’t give users the drowsy feeling known from other cannabis strains that contain CBD or THC. This cannabinoid, found primarily in C.indica and landrace strains from Africa and Asia, as well as various low-THC strains, is coming to the fore.
This is how cannabidivarin works
Although researchers are still working to decipher the full value of CBDV, the results of pre-tests show that it holds impressive potential for the human body. Like other cannabinoids like CBD, CBDV doesn’t have a very high correlation for cannabinoid receptors like CB1 and CB2.
It doesn’t have that high affinity, which explains why people don’t experience intoxicating feelings when ingesting which is familiar with cannabis.
According to recent studies, like CBD, cannabidivarin may act by other chemical pathways and mix indirectly with the body’s endocannabinoid system. Here is an example:
Clinical studies on the effectiveness of cannabidivarin in the treatment of epilepsy and convulsions show that the substance activates and desensitizes the body’s own TRPV1 receptors. The TRPV1 receptors play a vital role in our body’s ability to feel pain and temperature. At the same time, other tests show that CBDV can act on TRPVA1 and TRPVA2 receptors.
The receptors are all temporary channels that are constricted into the cell membrane, and when activated, they allow ions such as sodium to enter the body’s cells. When vital minerals like sodium get into the body quickly, the person ingesting CBDV will benefit from all of the sodium and other nutrients they have to offer.
The benefits of cannabidivarin
Much research on CBDV has focused on the effects it has on seizures, and it is for this reason that large pharmaceutical companies are investing in test studies to see how good this compound is in treating or preventing seizures.
GW Pharmaceuticals developed the first FDA-cleared CBD drug called “Epidiolex,” which was developed as a CBDV-based drug called GPW2006 to reduce and prevent epilepsy-induced seizures and other seizures.
Cannabidivarin influences the body’s own neurochemical pathway of the capsaicin receptors, which is at the beginning and in the course of various types of epilepsy. GW Pharmaceuticals claims that CBDV has shown anti-epileptic results in a variety of in vitro and vivo types of epilepsy.
A 2018 study in rodents showed that cannabidivarin helps with neurological behavior associated with Rett syndrome. Now Rett syndrome occurs when the X chromosome mutates and affects girls with seizures, muscle spasms, and language problems.
Cannabidivarin can help with both the genetic and chemically induced types of this particular disease.
According to an animal study and test conducted in the Journal in Psychopharmacology in 2019, it was reported that CBDV could rescue memory disorders in mice. The test used mice with the same genetic defects as most humans (those with Rett syndrome0). With CBDV, such neurological defects and effects can be gradually reduced.
In a study recently published in the British Journal of Pharmacology, it was reported that CBDV could be helpful in patients diagnosed with Duchenne muscular dystrophy (DMD). This disease enables irreversible skeletal muscle damage and chronic inflammation in the human body.
When CBDV is used, it can reduce inflammation, restore and improve muscle function in the body, and promote locomotion. Patients with joint pain may experience some relief after being given CBDV. Cannabidivarin also has the potential to be a novel therapy for treating DMD.
Both persistent childhood epilepsy and autism spectrum disorder occur simultaneously, and experts view CBDV as a potential treatment. Cannabidivarin can reduce some of the symptoms associated with health problems such as cognitive challenges, inconsistent behavior problems, communication and function problems.
CBDV has shown some potential as an effective anti-nausea agent through testing on rodents. Cannabidivarin has been shown to work against the CB1 receptors, thereby blocking the body’s nausea response.
A drug with such enormous potential also raises the question: “Does it have side effects?” No side effects have been identified with CBDV, but more research is needed to maintain this standard.
Cannabidivarin was discovered over 50 years ago and one will wonder, “Why are we just researching and testing it?” The cannabis plant itself is still being tested as the world tries to understand how it adds value to the health and wellness sector.
Cannabis has great potential in the medical industry, and cannabinoids are already playing a vital role in spreading this truth. You will hear and read more about cannabis and cannabinoids.
In the future, more cannabinoids will be discovered and explored, which confirms the truth that we have all accepted: cannabis is here to stay. For now, however, the focus is on cannabidivarin, and clinical studies have shown that the world is about to release this potent cannabinoid that will amplify the benefits of cannabis.
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