The Effect of Your Genes on Your Marijuana High

At some point you'll go out and a few drinks will probably seem different to you than usual… There are many different reasons for this, and genetics is one of them. The body is a complex system that scientists and doctors are still trying to understand. And when you add things to your body, you don't always know that it's going to react.

Like alcohol, marijuana has been around since early human history and has been used in worship, as medicine, and purely recreationally… but it remains unpredictable. Even experienced users have a variation of their usual path. But they can usually cope with marijuana's effects on them while remaining calm during an unpredictable high. However, things are different for newbies; Beginners usually cannot predict how the drug will affect them, whether it will result in a paranoid high or a fit of giggles.

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Cannabis works by binding to the cannabinoid receptors in our body, which are located in our cells and contain our individual DNA. Mutations in CB1 or CB2 receptors can make you more susceptible to various diseases such as Chron's disease or anorexia. These changes could also affect how your cells bind to different molecules, including those in cannabis. This is one explanation for why different people react differently to the same strain.

In a study published in the journal Nature Neuroscience, researchers found that a variable in the CHRNA2 gene may increase the risk of cannabis addiction. Cannabis addiction is something that is not fully understood and many people doubt that it exists. Symptoms of marijuana withdrawal include depression, irritability, a higher heart rate, and more.

While this gene doesn't determine whether someone is addicted to marijuana or not, it does increase the likelihood of such reactions to heavy use of the drug.

Photo by VICTOR HABBICK VISIONS/SCIENCE PHOTO LIBRARY/Getty Images

This all means that some of them may have slightly different reactions when sharing a bong or joint with friends, depending on several factors, including their genome, their personal experience with the drug, and the strain they are consuming.

Genes are extremely complex. Although we are born with some genetic mutations, due to the things we are exposed to throughout our lives, such as: B. the foods we eat, the germs we interact with, our stress levels and more, other mutations occur.

RELATED: Marijuana Makes You Paranoid? Study suggests your genes are to blame

There's a lot we don't yet understand about genetics, but organizations like the Allen Institute are conducting research to understand more. This will lead to a better understanding of cannabis and its effects on our genes. Once you start playing around with these variables, many possibilities arise that will hopefully lead to more medicinal and recreational benefits.

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