The 10 Best Selling Weed Strains of 2022

The end of the year is the time to wrap up, show off your Spotify Wrapped and swap favorites with friends. Our strain database continues to grow with over 6,000 entries and counting, so we created our own playlist whose strains have shot to the top of pharmacy lists and stayed there all year round.

At Leafly, we love having a firm grip on the cannabis pulse – what’s hot, what’s the hype, and what people are actually buying. Similar looking? Leafly’s best-selling strains of 2022 are proven classics that have all stood the test of time and stood the test of time, thanks to solid genetics, cultural support, and consistently delicious effects.

ice cream cake

Ice Cream Cake marijuana strainice cream cake. (David Downs/Leafly)

Some strain names lack explanation, but Ice Cream Cake is named perfectly – it’s a sugary, sweet smoke with notes of vanilla and musky with a gassy kick. Smoking also tends to evoke that childlike joy you felt when the ice cream truck pulled up.

This creation by Seed Junky Genetics combines Gelato #33 and Wedding Cake, both also on this list, into a strain that never skimps on experience, appeal, or flavor. It’s an easy number one spot for Leafly buyers and connoisseurs, and took first place in the Emerald Cup twice, in 2019 and 2021. We also featured it as a Leafly July highlight.

blue dream

Blue Dream has always been easy on the eyes.  (David Downs/Leafly)Blue Dream has always been easy on the eyes. (David Downs/Leafly)

Love it, hate it, our #2 bestselling Blue Dream is going nowhere! Blueberry and Haze make for a sweet, fruity, herbaceous hybrid that might surprise you with its creative head high and body stone. It’s always affordable, widely available, and consistent—is it fair to call Blue Dream the better-tasting Bud Light of weed?

Caleb Chen, founder and editor of cannabis review blog The Highest Critic, says he’s recently tried Blue Dream again after many years of dislike.

“Blue Dream is undoubtedly better now. It hit all the nostalgic notes and then some. [The high] was inspirational, good taste; a pleasant daydream.”


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wedding cake

(David Downs/Leafly)

It’s actually called Wedding Cake (or Pink Cookies, for Canadians) because the first hit will have your head ringing like a ceremonial bell while a pungent aroma of sweet vanilla dough, menthol, and a pinch of pine fills your sinuses. Seed Junky stays on this list with its combination of Triangle Kush and Animal Mints, which we and the public loved so much that we named it Strain of the Year 2019. Lasting love keeps it in the top three. The third biggest effect of the wedding cake is excitement – and that shouldn’t be overlooked. Rawr.


Ice c. 2015. (David Downs)Ice c. 2015. (David Downs)

Gelato has its place in the proverbial cannabis hall of fame for its airy vanilla creamy palate; We named her Strain of the Year for 2018 for her flavor, showy royal purple buds, and deeply euphoric chill. Sunset Sherbert by Sherbinski and Thin Mint GSC by Cookie Fam created the strain that has produced thousands of crosses that win cannabis competitions everywhere, every year.

G, founder of East Coast cannabis brand Lizm, says their ubiquity means, “Gelato is the new sour. The palate has changed. So many [strains] have that gelato taste” — that caryophyllene-fueled concoction of sugar, funk, and diesel. At #4 he is not wrong!

original glue

Original Glue marijuana strain(David Downs/Leafly)

When Sours ruled the cannabis game, Original Glue, aka GG#4, was the prom king. It breaks through the musky earthiness and body-melting effects of Kush to offer a snappy daytime high with rich thorny, almost onion-like terpenes. The late great Josey Whales and co-creator Lone Watie bred Original Glue from a heady blend of Chem’s Sister, Sour Dubb and Chocolate Diesel.

Xochitl Segura-Garcia, cannabis industry expert and social media personality, loves it, telling Leafly that “GG it’s such a big foundation for so many strains. It’s its own little shining star.” It was also honored with first place at the 2014 Cannabis Cups in Michigan and Los Angeles. Not bad to round out the top 5.

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Pineapple Express

asked Weed(Courtesy of Leafly)

Seth Rogen cemented Pineapple Express in stoner history forever, but this tropical sativa has stayed on pharmacy shelves because it tastes like a Jamba Juice smoothie and smokes like a pre-workout shot.

At number 6, Pineapple Express proves that people love sativas for their creative zeal and pungent terpenes, although rocky hybrids still reign supreme. G-13 Labs combined Big Bud and Hawaiian for a cerebral buzz that would make you brave enough to blow up a grow operation.

Sour diesel

Uncle Jesse's East Coast Sour Diesel.  (David Downs/Leafly)East Coast Sour Diesel grown by Uncle Jesse. (David Downs/Leafly)

Smoking Sour Diesel means literally pumping the gas into your cerebral engine. East Coast tastemakers bred Sour Diesel from Chemdawg and Super Skunk to have a strong diesel nose that’s skunky on the tongue – with Bugatti-level buds in electric green. New York made her famous in the ’90s, but she and her iterations are hugely popular across the country today, and she holds up at number 7 among the more modern strains. Mikhail Harrison, a Leafly contributor and connoisseur says, “It’s a lost gem! I would be willing to pay $1,000 for an ounce of real Sour Diesel.”


Stock up on Sour Diesel for New Year’s Eve – December’s Leafly HighLight


MAC marijuana strainMAC made out of LA. (David Downs/Leafly)

No cap, this variety smacks. MAC hit the cannabis scene much like the Trucks – hard – due to her pungent garlicky terpenes with hints of citrus and the ability to knock out the most seasoned stoners. When you’re in pain or staying home overnight, this elegant stew of Starfighter, Columbian and Alien Cookies, bred by the incomparable Capulator, hits the spot. She’s one of the youngest strains on this list, but still holds her spot at number 8.

This is a strain for true connoisseurs – she took second place in two different categories at the 2020 Oregon Cannabis Cup, and eighth of those have sold for up to $100.

Purple punch

A macro bud shot of icy purple and green Purple Punch (David Downs/Leafly)A macro bud shot of icy purple and green Purple Punch (David Downs/Leafly)

Before you judge, what has Purple Punch ever done to you? This indica-dominant strain retains the Kool-Aid grapey flavor that made purple strains famous, while imparting a high that will chill you out and won’t glue you to the couch. Her two parents, Grandaddy Purple and Larry OG, also ensure that she is a real eye-catcher, with purple buds laced with green and trichome ripening. Symbiotic genetics deserve credit – without Purple Punch we wouldn’t have afternoon delights like Mimosa or Wedding Crasher. It’s not a top fiver, but Purple Punch clearly has some fans at number 9.

Durban Poison

Durban Poison from Whitethorn Valley Farm – via Farm Cut (David Downs/Leafly)Durban Poison from Whitethorn Valley Farm – via Farm Cut (David Downs/Leafly)

The only toxic thing about Durban Poison is how underrated it is. This landrace sativa (read, pure sativa) fires up your neural synapses with a rich, resinous nose of black pepper and pine. Hailing from the port city of Durban, South Africa, Durban Poison is a multiple Cannabis Cup winner and one of the parent strains of the much-loved Thin Mints GSC. Even at number 10, Durban Poison plays a big part in hemp history.

G from Lizm thinks it’s like Mick Jagger or Gene Simmons — you still love them even though they’re past their peak of popularity because they’re still rocking.

Amelie Williams

New York-based freelance cannabis journalist Amelia Williams is a graduate of San Francisco State University’s journalism program and a former budtender. Williams has contributed to GreenState, MG Magazine, Culture Magazine and Cannabis Now, Kirkus Reviews and The Bold Italic of the San Francisco Chronicle.

Check out Amelia Williams’ articles

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