The latest about medical marijuana and migraines

You can destroy a day in seconds … but can marijuana help with migraines?

You can sometimes climb a day when you arrive and devastate in the long run. So what is the latest on medical marijuana and migraines? A wave of fresh research throws a new light on the potential of medical marijuana as the treatment of migraines, with the weakening neurological state concerns about 15% of people worldwide or almost 1 billion people. In the United States, lifelong incidence is around 43% for women and 18% for men.

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The detection of migraines remains of crucial importance for prompt intervention. The classic characters include a pulsating, moderate to severe headache, which is typically one -sided and is often accompanied by nausea and hypersensitivity to light (photophobia) and sound (phonophobia). Attacks can take 4 to 72 hours and many affected people go through Prodromal symptoms -Mood changes, fatigue or neck pain -before the headache phase.

In a pioneering, placebo-controlled clinical study, which was presented at the annual conference of the American Headache Society 2025, researchers from UC San Diego showed a precise mix of 6% THC and 11% CBD to a significant migrene easier:

• 67.2% of the participants had received the placebo in 2 hours of pain relief compared to ~ 46.6%.
• 34.5% achieved full freedom of pain, compared to 15.5% with placebo.
• The advantages were preserved for 24 hours for pain relief and 48 hours to relieve their most annoying symptoms, including light or sound sensitivity.

The investigators emphasized how important controlled, rare doses – the use of less than ten times a month – to avoid medication over -claimed headaches (MOH) and reduce the risks of psychoactive effects.

A systematic review that covered almost 2,000 migraine patients showed that medical cannabis reduced the monthly headache frequency from 10.4 to 4.6 days – a remarkable waste of ~ 56%. It also relieved the associated nausea and vomiting, with the effects comparable to amitriptylin when reducing the frequency (~ 40%).

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Surface -based studies reflect these results:

• In a register, the patients reported that the severity of cannabis migraines halved, although the effectiveness decreased over time.
• Another review confirmed that medical marijuana significantly reduces both the length and the frequency of migraines, without severe undesirable events (cannabisclinician.org).

Despite promising results, more research is required. A retrospective study showed that cannabis use increased the prevalence of headaches (overborn in medication). Slight side effects – such as sleepiness, drowsiness or cognitive blips – are recorded in up to 43.75% of users, especially in the case of oral forms.