The best cannabinoids for colon cancer

Cannabis contains phytocannabinoids, molecules with properties ranging from intoxicating to therapeutic. Cannabinoids use multiple strategies to fight off various cellular malignancies, including oral and colon cancer.

A pharmaceutical company published research in collaboration with the Sourasky Medical Center in Tel Aviv in 2020. This previous study found benefits of cannabichromene (CBC) and cannabigerol (CBG) for the treatment of gastrointestinal cancer. Their latest paper examines how effective cannabinoids are at killing colon cancer, the third most common cancer in the United States. (1)

THC and CBG or CBD for colon cancer

Swedish researchers once killed colon cancer using CBG’s anti-inflammatory and cytotoxic mechanisms. (2) Following their 2020 study, the Israeli company recently explored other cannabinoids against cancer. But delta-8 and delta-9 THC were instead found to be the most effective at killing colon cancer.

CBD was effective in preventing cell clusters in the colon known as polyps. Cannabidiol was less effective at slowing the spread of colon cancer cells. However, several other cannabinoids produced a symphony of anti-cancer effects.

Personalized canna medicine

Cannabinoids do not treat every type of cancer. And various cannabinoids are only cytotoxic, or therapeutic, against certain types of cell mutations. The recent study by a pharmaceutical company found anti-cancer properties in phyto-, but also in synthetic cannabinoids.

Clinicians ideally design cancer treatments around each individual’s complex immune system. This means that the most effective cannabinoid or synergistic blend of cannabis compounds for colon cancer depends on the individual.

Let us know in the comments if you’ve treated cancer with cannabinoids.

Sources

1. Ben-Ami Shor, D.; Hochmann, I.; luck, N.; Shibolet, O.; Scapa, E. The cytotoxic effect of isolated cannabinoid extracts on polypoid colorectal tissue. international J Mol Science. 2022, 23, 1366. doi/10.3390/ijms231911366
2. Ruhaak LR, Felth J, Karlsson PC, Rafter JJ, Verpoorte R, Bohlin L. Evaluation of the cyclooxygenase inhibitory effects of six major cannabinoids isolated from Cannabis sativa. Biol PharmBull. 2011;34(5):774-778. doi:10.1248/bpb.34.774

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