Can Magic Mushrooms Treat Overeating? New clinical study to find out

Of Natan Ponyman

Psilocybin, the active ingredient in magic mushrooms, could be part of the solution for people struggling with binge eating disorder, a condition characterized by recurring episodes of eating large amounts of food and that There is a feeling of not being able to stop.

Tryp Therapeutics, Inc., a psychedelic biotechnology company, has dosed the first patient in a Phase 2 study evaluating this psychedelic compound in the treatment of binge eating disorder (BED).

Photo by Carles Rabada via Unsplash

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The study also includes psychotherapy using protocols developed in collaboration with Fluence, a psychedelics education and research platform. According to Tryp, nearly 30% of people seeking weight loss treatment show signs of this condition.

As covered by Benzinga, Tryp received approval to conduct the study in December 2021. The study used TRP-8802, a 25 mg synthetic psilocybin oral capsule that was designed without IP protection.

The company chose to use a non-proprietary version of the drug “to quickly initiate clinical trials to generate initial data” while also developing an improved, proprietary formulation and delivery system for psilocybin called TRP-8803.

“This is a key study for our psilocybin-assisted therapy portfolio as we evaluate the effectiveness of TRP-8802 (orally administered psilocybin) in treating patients with BED,” said Dr. Jim Gilligan, Chief Scientific Officer and interim CEO of Tryp Therapeutics.

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“We believe psilocybin-assisted therapy has the potential to offer a new therapeutic treatment for BED, a disorder that devastates the lives of over 250,000 people each year,” Gilligan added.

This article originally appeared on Benzinga and has been republished with permission.

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